Inulin alleviates atherosclerosis through improving lipid metabolism, inflammation, and gut microbiota in ApoE-knockout mice: the short-chain is more efficacious.
We investigated how inulin, a type of fiber, affects atherosclerosis, a condition that can lead to serious heart and brain problems. Using ApoE-knockout mice fed a high-fat diet, we tested the effects of two forms of inulin: short-chain and long-chain. By administering these types of inulin for 12 weeks, we aimed to understand their impact on lipid metabolism, inflammation, and gut health.
Our findings revealed that inulin can help protect against atherosclerosis. Specifically, short-chain inulin proved to be more effective than its long-chain counterpart. We saw improvements in lipid metabolism, reduced inflammation, and healthier gut microbiota. This suggests that when it comes to using inulin as a dietary intervention for heart health, short-chain inulin stands out as the more promising option.
Overall, this study highlights the potential of inulin to play a role in managing cardiovascular health, with implications for dietary recommendations. It’s exciting to consider how incorporating this fiber into our diets might support cardiovascular well-being.
Read More
9
Dietary inulin reduces hypertension
High-Soluble-Fiber Diet Attenuates Hypoxia-Induced Vascular Remodeling and the Development of Hypoxic Pulmonary Hypertension.
We explored the effects of a high-soluble-fiber diet, specifically inulin, on cardiovascular health, particularly concerning a condition known as hypoxic pulmonary hypertension. In this study, mice were fed either a low or high-soluble-fiber diet and then exposed to hypoxic conditions to see how these diets influenced pulmonary pressure and vascular resistance.
Our findings indicated that a diet rich in soluble fiber not only reduced right ventricular systolic pressure but also improved pulmonary vascular resistance in the hypoxic mice. We observed that this dietary change led to an increase in beneficial gut bacteria that produce short-chain fatty acids, along with changes in levels of various metabolites in the blood. Notably, there was a reduction in inflammatory cells in the lungs, suggesting that inulin may play a role in managing inflammation tied to pulmonary hypertension.
This study sheds light on the potential of dietary adjustments, specifically an increase in soluble fiber, in mitigating pulmonary hypertension – a significant finding for understanding cardiovascular health in stressful conditions.
Read More
8
Inulin reduces atherosclerosis risk
The effect and mechanism of inulin on atherosclerosis is mediated by the characteristic intestinal flora and metabolites.
We conducted an intriguing study to see how inulin, a type of prebiotic, affects atherosclerosis—a condition that can lead to heart disease. Using a mouse model that mimicked human responses to a high-fat diet, we divided 30 mice into three groups: one group received a normal diet, another a high-fat diet, and the last group a high-fat diet supplemented with inulin.
After 16 weeks, we made some fascinating observations. Inulin treatment appeared to significantly inhibit the formation of atherosclerotic plaques. We believe this is due to inulin's positive influence on lipid metabolism and its ability to alter the composition of the intestinal microbiota, which produces beneficial metabolites.
Moreover, we found that inulin may help reduce inflammation linked to cardiovascular disease. This might provide a dual approach—improving gut health while combating harmful effects on the heart and blood vessels. Our findings underscore the potential of using dietary interventions like inulin to modify not just gut health, but also cardiovascular health by adjusting the microbial community and its metabolites.
Read More
Most Useful Reviews
9
Positive results noted
8 people found this helpful
Excellent! This is a remarkable supplement for a child with autism. We administer inulin as per the Nemechek protocol and have observed positive results. It effectively regulates intestinal function – easing constipation and strengthening diarrhoea, depending on the dosage. The taste is sweet, and it dissolves well in both drinks and food.
Read More
7.5
Great for digestion
3 people found this helpful
Inulin powder is just what I need for my cardiovascular system and digestion! I buy it regularly. The composition is excellent, with nothing but inulin, and the large jar lasts a long time. It doesn't require refrigeration, making it easy to take continuously. The powder dissolves well in warm drinks; I often add it to my tea or coffee for a sweet taste. The benefits to my health are immense, and I will definitely repurchase once I finish my jar.
Read More
9
Lowered cholesterol levels
Everything stated here is true; I've experienced it myself! My cholesterol dropped from 7.7 to 6.5. Inulin is a natural polysaccharide that behaves like fibre and has many healing benefits. It normalizes gastrointestinal function, promotes beneficial microorganisms, and can aid in appetite control and weight loss. Inulin also lowers cholesterol production in the liver, showing a positive effect on overall health, especially the cardiovascular system, while boosting immune defences by normalising gut function. It’s important to remember that while beneficial for diabetes, Inulin can raise blood sugar levels, so please consult your doctor before use.
Inulin alleviates atherosclerosis through improving lipid metabolism, inflammation, and gut microbiota in ApoE-knockout mice: the short-chain is more efficacious.
We investigated how inulin, a type of fiber, affects atherosclerosis, a condition that can lead to serious heart and brain problems. Using ApoE-knockout mice fed a high-fat diet, we tested the effects of two forms of inulin: short-chain and long-chain. By administering these types of inulin for 12 weeks, we aimed to understand their impact on lipid metabolism, inflammation, and gut health.
Our findings revealed that inulin can help protect against atherosclerosis. Specifically, short-chain inulin proved to be more effective than its long-chain counterpart. We saw improvements in lipid metabolism, reduced inflammation, and healthier gut microbiota. This suggests that when it comes to using inulin as a dietary intervention for heart health, short-chain inulin stands out as the more promising option.
Overall, this study highlights the potential of inulin to play a role in managing cardiovascular health, with implications for dietary recommendations. It’s exciting to consider how incorporating this fiber into our diets might support cardiovascular well-being.
Read More
9
Dietary inulin reduces hypertension
High-Soluble-Fiber Diet Attenuates Hypoxia-Induced Vascular Remodeling and the Development of Hypoxic Pulmonary Hypertension.
We explored the effects of a high-soluble-fiber diet, specifically inulin, on cardiovascular health, particularly concerning a condition known as hypoxic pulmonary hypertension. In this study, mice were fed either a low or high-soluble-fiber diet and then exposed to hypoxic conditions to see how these diets influenced pulmonary pressure and vascular resistance.
Our findings indicated that a diet rich in soluble fiber not only reduced right ventricular systolic pressure but also improved pulmonary vascular resistance in the hypoxic mice. We observed that this dietary change led to an increase in beneficial gut bacteria that produce short-chain fatty acids, along with changes in levels of various metabolites in the blood. Notably, there was a reduction in inflammatory cells in the lungs, suggesting that inulin may play a role in managing inflammation tied to pulmonary hypertension.
This study sheds light on the potential of dietary adjustments, specifically an increase in soluble fiber, in mitigating pulmonary hypertension – a significant finding for understanding cardiovascular health in stressful conditions.
Read More
8
Inulin reduces atherosclerosis risk
The effect and mechanism of inulin on atherosclerosis is mediated by the characteristic intestinal flora and metabolites.
We conducted an intriguing study to see how inulin, a type of prebiotic, affects atherosclerosis—a condition that can lead to heart disease. Using a mouse model that mimicked human responses to a high-fat diet, we divided 30 mice into three groups: one group received a normal diet, another a high-fat diet, and the last group a high-fat diet supplemented with inulin.
After 16 weeks, we made some fascinating observations. Inulin treatment appeared to significantly inhibit the formation of atherosclerotic plaques. We believe this is due to inulin's positive influence on lipid metabolism and its ability to alter the composition of the intestinal microbiota, which produces beneficial metabolites.
Moreover, we found that inulin may help reduce inflammation linked to cardiovascular disease. This might provide a dual approach—improving gut health while combating harmful effects on the heart and blood vessels. Our findings underscore the potential of using dietary interventions like inulin to modify not just gut health, but also cardiovascular health by adjusting the microbial community and its metabolites.
Read More
8
Inulin supports cardiovascular health
The Dietary Fiber Inulin Slows Progression of Chronic Kidney Disease-Mineral Bone Disorder (CKD-MBD) in a Rat Model of CKD.
We investigated how inulin, a type of fermentable dietary fiber, impacts cardiovascular health in a model of chronic kidney disease (CKD). In our study, we fed rats with CKD a diet containing either 10% inulin or cellulose, another type of fiber, to compare their effects on heart and blood vessel health. Over several weeks, we kept track of various health markers, including heart function and levels of certain hormones related to kidney disease.
Our results were promising. We observed that inulin slowed the deterioration of cardiovascular health in the rats, specifically reducing factors like aortic and cardiac calcification, which are indicators of heart disease. This fiber did not seem to affect kidney function, suggesting that its benefits might be linked to changes in gut bacteria and decreased levels of harmful toxins produced by the gut.
While inulin showed positive effects on heart health in the context of CKD, it is important to note that no significant improvements were seen in all measures of bone health or kidney function. Overall, the findings suggest that adding inulin to the diet could be a simple yet effective way to support cardiovascular health in individuals with chronic kidney conditions.
Read More
7
Inulin's effects on heart health
The effects of inulin-type fructans on cardiovascular disease risk factors: systematic review and meta-analysis of randomized controlled trials.
We aimed to understand how inulin-type fructans (ITF) might influence cardiovascular disease risk factors in adults. To answer this question, we delved into a series of randomized controlled trials that compared ITF supplementation with a placebo.
Our analysis covered various health markers, such as cholesterol levels—both low-density (LDL) and high-density (HDL)—triglycerides, blood glucose levels, and measures of weight and blood pressure. We found that ITF may help to reduce low-density lipoprotein cholesterol, triglycerides, and body weight, which are all key players in cardiovascular health.
However, it’s important to note that the confidence in these findings is low to very low. This means further, more robust studies are necessary to firmly establish the benefits of ITF in reducing cardiovascular disease risks. Our exploration highlights a promising area of research, though we need to proceed with caution before drawing any definitive conclusions.
Excellent! This is a remarkable supplement for a child with autism. We administer inulin as per the Nemechek protocol and have observed positive results. It effectively regulates intestinal function – easing constipation and strengthening diarrhoea, depending on the dosage. The taste is sweet, and it dissolves well in both drinks and food.
Read More
7.5
Great for digestion
3 people found this helpful
Inulin powder is just what I need for my cardiovascular system and digestion! I buy it regularly. The composition is excellent, with nothing but inulin, and the large jar lasts a long time. It doesn't require refrigeration, making it easy to take continuously. The powder dissolves well in warm drinks; I often add it to my tea or coffee for a sweet taste. The benefits to my health are immense, and I will definitely repurchase once I finish my jar.
Read More
9
Lowered cholesterol levels
Everything stated here is true; I've experienced it myself! My cholesterol dropped from 7.7 to 6.5. Inulin is a natural polysaccharide that behaves like fibre and has many healing benefits. It normalizes gastrointestinal function, promotes beneficial microorganisms, and can aid in appetite control and weight loss. Inulin also lowers cholesterol production in the liver, showing a positive effect on overall health, especially the cardiovascular system, while boosting immune defences by normalising gut function. It’s important to remember that while beneficial for diabetes, Inulin can raise blood sugar levels, so please consult your doctor before use.
Read More
7.5
Effective digestion aid
1 people found this helpful
My mother found inulin effective after just a week of taking it. Her symptoms of slow digestion and constipation improved significantly, as evidenced by her stomach's sounds. I renewed my subscription to help further ease her constipation problem, hoping it will contribute to her digestive health.
Read More
9
Lowers cholesterol levels
Inulin is a natural prebiotic with numerous benefits. It normalises the gastrointestinal tract by promoting beneficial microorganisms and reducing constipation. Studies indicate that it also aids appetite control and weight loss. Inulin lowers cholesterol levels by affecting liver enzymes and enhancing cholesterol elimination from the body, positively impacting the cardiovascular system while improving digestive health.
Read More
Frequently Asked Questions
Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.
Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.
Prebiotic fiber inulin is a naturally occurring carbohydrate found in a variety of plants, particularly in roots and tubers such as chicory, garlic, leeks, and onions. As a soluble fiber, it is not digested in the small intestine but rather fermented by beneficial gut bacteria in the large intestine. This fermentation process helps promote the growth of beneficial bacteria, which can support gut health, improve digestion, and enhance the absorption of certain nutrients. Increasing dietary intake of prebiotic fibers like inulin can contribute to a healthier microbiome.
In addition to its benefits for gut health, inulin can also help to enhance feelings of fullness and reduce appetite, making it a popular ingredient in weight management products. It is often added to food and beverage items as a texturizer or sweetener because it offers a mildly sweet flavor without contributing significant calories. Given its numerous health benefits, inulin is frequently emphasized in discussions about dietary fiber and overall nutrition, making it a valuable component of a balanced diet.
Based on user reviews, it appears that individuals taking inulin for cardiovascular health may begin to notice benefits within a comparatively short time frame. One user mentioned experiencing a significant drop in cholesterol levels after approximately 2 months of use, indicating a positive impact on cardiovascular health (Read Review). Another user noted that their mother observed improvements in digestion within just a week, suggesting that while some effects may be felt relatively quickly, results on cardiovascular metrics like cholesterol may take longer to materialize (Read Review).
Overall, while the time it takes to see results can vary from person to person, users frequently report noticeable effects within one to two months of consistent use. Those using inulin for cardiovascular support may want to monitor their progress after this period to evaluate its effectiveness personally.
Inulin, a type of dietary fiber, has shown promise in various studies regarding cardiovascular health. For example, research indicates that inulin can help inhibit the formation of atherosclerotic plaques, improve lipid metabolism, and reduce inflammation, making it a potential ally in cardiovascular disease prevention [2]. Furthermore, in rat studies with chronic kidney disease, inulin was found to slow the deterioration of cardiovascular health and improve gut bacteria, indicating its protective effect on heart function [4].
While the initial findings are encouraging, it’s important to approach these results with caution. The confidence in outcomes related to inulin’s effectiveness in directly lowering cardiovascular disease risk factors has been described as low to very low in some studies [3]. Other research highlighted that while inulin can contribute positively to gut health and inflammation, its isolated benefits on cardiovascular diseases are still unclear, warranting further investigation [10]. Therefore, while there is scientific support for inulin's potential role in cardiovascular health, more robust research is needed to confirm its efficacy and establish specific guidelines for use.
Many users report experiencing a variety of improvements in symptoms after incorporating inulin into their diets, particularly related to digestive health and cardiovascular benefits. One user noted significant relief from constipation and slow digestion within just a week of use, leading them to continue with the supplement to further support digestive function Read Review. Another user, who adhered to the Nemechek protocol for a child with autism, found that inulin effectively regulated intestinal function, adapting to ease constipation or strengthen diarrhea based on dosage Read Review.
In terms of cardiovascular health, users report promising results such as a noticeable drop in cholesterol levels, with one individual transitioning from a cholesterol reading of 7.7 to 6.5 while using inulin regularly Read Review. Consistent feedback highlights inulin's role in promoting beneficial microorganisms in the gut, which appears to aid not only in digestion but also in overall well-being. While these experiences indicate that users perceive positive changes, it's important to remember that individual results can vary based on personal health circumstances and adherence to dosage recommendations.
Users who have reported on their experiences with inulin often mention combining it with other supplements, such as following specific dietary protocols like the Nemechek protocol for managing health conditions. While explicit details on combinations with other supplements are limited, several users emphasize the singular benefits of inulin itself, particularly its positive impact on cardiovascular health. For instance, one user noted a significant drop in cholesterol levels while taking inulin, suggesting its effectiveness in promoting heart health (Read Review). Another user appreciates the supplement's ability to improve both cardiovascular function and digestive health, indicating it seems to work well independently without negative interactions (Read Review).
Overall, while many users comment on inulin's strong benefits, particularly for cardiovascular health, there isn't a substantial number of reviews that detail specific combinations with other supplements. Instead, the focus appears to be primarily on inulin's standalone effects on health metrics such as cholesterol levels and digestive improvement. Users are encouraged to consult healthcare professionals for tailored advice on supplement combinations to address cardiovascular concerns effectively.
Based on user reviews, there doesn't seem to be a specific recommended dose for Prebiotic Fiber Inulin when it comes to treating cardiovascular disease. However, users report witnessing significant benefits, such as lowered cholesterol levels and improved digestive health. One user noted a personal experience where their cholesterol dropped from 7.7 to 6.5 after incorporating inulin into their routine, highlighting its potential positive effects on the cardiovascular system Read Review. Another reviewer emphasized the benefits to their cardiovascular system and overall health, reinforcing the idea that regular consumption of inulin can lead to immune and digestive health improvements Read Review.
Additionally, users suggest that inulin can help modulate gastrointestinal functions, which plays a role in overall health, including cardiovascular wellness. While specific dosing was not universally discussed across reviews, the general sentiment supports a continuous use of inulin for health benefits, advising users to consult their doctors, especially if they have predefined health concerns like diabetes that inulin might affect Read Review.
9
Lowered cholesterol levels
Everything stated here is true; I've experienced it myself! My cholesterol dropped from 7.7 to 6.5. Inulin is a natural polysaccharide that behaves like fibre and has many healing benefits. It normalizes gastrointestinal function, promotes beneficial microorganisms, and can aid in appetite control and weight loss. Inulin also lowers cholesterol production in the liver, showing a positive effect on overall health, especially the cardiovascular system, while boosting immune defences by normalising gut function. It’s important to remember that while beneficial for diabetes, Inulin can raise blood sugar levels, so please consult your doctor before use.
7.5
Effective digestion aid
1 people found this helpful
My mother found inulin effective after just a week of taking it. Her symptoms of slow digestion and constipation improved significantly, as evidenced by her stomach's sounds. I renewed my subscription to help further ease her constipation problem, hoping it will contribute to her digestive health.
9
Positive results noted
8 people found this helpful
Excellent! This is a remarkable supplement for a child with autism. We administer inulin as per the Nemechek protocol and have observed positive results. It effectively regulates intestinal function – easing constipation and strengthening diarrhoea, depending on the dosage. The taste is sweet, and it dissolves well in both drinks and food.
7.5
Great for digestion
3 people found this helpful
Inulin powder is just what I need for my cardiovascular system and digestion! I buy it regularly. The composition is excellent, with nothing but inulin, and the large jar lasts a long time. It doesn't require refrigeration, making it easy to take continuously. The powder dissolves well in warm drinks; I often add it to my tea or coffee for a sweet taste. The benefits to my health are immense, and I will definitely repurchase once I finish my jar.
9
Lowers cholesterol levels
Inulin is a natural prebiotic with numerous benefits. It normalises the gastrointestinal tract by promoting beneficial microorganisms and reducing constipation. Studies indicate that it also aids appetite control and weight loss. Inulin lowers cholesterol levels by affecting liver enzymes and enhancing cholesterol elimination from the body, positively impacting the cardiovascular system while improving digestive health.
8
Inulin reduces atherosclerosis risk
The effect and mechanism of inulin on atherosclerosis is mediated by the characteristic intestinal flora and metabolites.
We conducted an intriguing study to see how inulin, a type of prebiotic, affects atherosclerosis—a condition that can lead to heart disease. Using a mouse model that mimicked human responses to a high-fat diet, we divided 30 mice into three groups: one group received a normal diet, another a high-fat diet, and the last group a high-fat diet supplemented with inulin.
After 16 weeks, we made some fascinating observations. Inulin treatment appeared to significantly inhibit the formation of atherosclerotic plaques. We believe this is due to inulin's positive influence on lipid metabolism and its ability to alter the composition of the intestinal microbiota, which produces beneficial metabolites.
Moreover, we found that inulin may help reduce inflammation linked to cardiovascular disease. This might provide a dual approach—improving gut health while combating harmful effects on the heart and blood vessels. Our findings underscore the potential of using dietary interventions like inulin to modify not just gut health, but also cardiovascular health by adjusting the microbial community and its metabolites.
8
Inulin supports cardiovascular health
The Dietary Fiber Inulin Slows Progression of Chronic Kidney Disease-Mineral Bone Disorder (CKD-MBD) in a Rat Model of CKD.
We investigated how inulin, a type of fermentable dietary fiber, impacts cardiovascular health in a model of chronic kidney disease (CKD). In our study, we fed rats with CKD a diet containing either 10% inulin or cellulose, another type of fiber, to compare their effects on heart and blood vessel health. Over several weeks, we kept track of various health markers, including heart function and levels of certain hormones related to kidney disease.
Our results were promising. We observed that inulin slowed the deterioration of cardiovascular health in the rats, specifically reducing factors like aortic and cardiac calcification, which are indicators of heart disease. This fiber did not seem to affect kidney function, suggesting that its benefits might be linked to changes in gut bacteria and decreased levels of harmful toxins produced by the gut.
While inulin showed positive effects on heart health in the context of CKD, it is important to note that no significant improvements were seen in all measures of bone health or kidney function. Overall, the findings suggest that adding inulin to the diet could be a simple yet effective way to support cardiovascular health in individuals with chronic kidney conditions.
7
Inulin's effects on heart health
The effects of inulin-type fructans on cardiovascular disease risk factors: systematic review and meta-analysis of randomized controlled trials.
We aimed to understand how inulin-type fructans (ITF) might influence cardiovascular disease risk factors in adults. To answer this question, we delved into a series of randomized controlled trials that compared ITF supplementation with a placebo.
Our analysis covered various health markers, such as cholesterol levels—both low-density (LDL) and high-density (HDL)—triglycerides, blood glucose levels, and measures of weight and blood pressure. We found that ITF may help to reduce low-density lipoprotein cholesterol, triglycerides, and body weight, which are all key players in cardiovascular health.
However, it’s important to note that the confidence in these findings is low to very low. This means further, more robust studies are necessary to firmly establish the benefits of ITF in reducing cardiovascular disease risks. Our exploration highlights a promising area of research, though we need to proceed with caution before drawing any definitive conclusions.
7
Functional foods and cholesterol management
Effect of a dietary intervention with functional foods on LDL-C concentrations and lipoprotein subclasses in overweight subjects with hypercholesterolemia: Results of a controlled trial.
We conducted a study focusing on how a dietary portfolio, including inulin, can influence cholesterol levels in overweight individuals with mild hypercholesterolemia. Our trial involved 62 participants who were split into groups to follow either a low saturated fat diet coupled with a placebo or the dietary portfolio for about two and a half months.
While we aimed to assess the effectiveness of the dietary intervention on LDL-C, which is a key cholesterol marker linked to cardiovascular health, the effects of inulin alone are difficult to pinpoint. The inclusion of inulin in the dietary portfolio did not provide conclusive evidence regarding its standalone impact on improving cardiovascular outcomes.
Overall, our findings suggest that incorporating functional foods into lifestyle changes could be beneficial for managing mild hypercholesterolemia. However, the isolated benefits of inulin on cardiovascular disease remain uncertain and require further investigation.
References
Zhang K, Zeng Y, Li J, Huang Y, Zhang N, et al. Inulin alleviates atherosclerosis through improving lipid metabolism, inflammation, and gut microbiota in ApoE-knockout mice: the short-chain is more efficacious. Front Pharmacol. 2024;15:1445528. doi:10.3389/fphar.2024.1445528
Li Z, Xu Q, Huangfu N, Cui H. The effect and mechanism of inulin on atherosclerosis is mediated by the characteristic intestinal flora and metabolites. Coron Artery Dis. 2024;35:498. doi:10.1097/MCA.0000000000001377
Talukdar JR, Cooper M, Lyutvyn L, Zeraatkar D, Ali R, et al. The effects of inulin-type fructans on cardiovascular disease risk factors: systematic review and meta-analysis of randomized controlled trials. Am J Clin Nutr. 2024;119:496. doi:10.1016/j.ajcnut.2023.10.030
Biruete A, Chen NX, Metzger CE, Srinivasan S, O'Neill K, et al. The Dietary Fiber Inulin Slows Progression of Chronic Kidney Disease-Mineral Bone Disorder (CKD-MBD) in a Rat Model of CKD. JBMR Plus. 2023;7:e10837. doi:10.1002/jbm4.10837
Pakhomov NV, Kostyunina DS, Macori G, Dillon E, Brady T, et al. High-Soluble-Fiber Diet Attenuates Hypoxia-Induced Vascular Remodeling and the Development of Hypoxic Pulmonary Hypertension. Hypertension. 2023;80:2372. doi:10.1161/HYPERTENSIONAHA.123.20914
Moleón J, González-Correa C, Robles-Vera I, Miñano S, de la Visitación N, et al. Targeting the gut microbiota with dietary fibers: a novel approach to prevent the development cardiovascular complications linked to systemic lupus erythematosus in a preclinical study. Gut Microbes. 2023;15:2247053. doi:10.1080/19490976.2023.2247053
Ruskovska T, Konic-Ristic A, Mazur A, Milenkovic D. Molecular mechanisms underlying hypertensive effect of fructose and the preventive properties of inulin - Global transcriptomic analysis in rat aorta. Nutr Metab Cardiovasc Dis. 2023;33:441. doi:10.1016/j.numecd.2022.11.009
Miralles-Pérez B, Nogués MR, Sánchez-Martos V, Fortuño-Mar À, Ramos-Romero S, et al. Influence of Dietary Inulin on Fecal Microbiota, Cardiometabolic Risk Factors, Eicosanoids, and Oxidative Stress in Rats Fed a High-Fat Diet. Foods. 2022;11. doi:10.3390/foods11244072
Companys J, Calderón-Pérez L, Pla-Pagà L, Llauradó E, Sandoval-Ramirez BA, et al. Effects of enriched seafood sticks (heat-inactivated B. animalis subsp. lactis CECT 8145, inulin, omega-3) on cardiometabolic risk factors and gut microbiota in abdominally obese subjects: randomized controlled trial. Eur J Nutr. 2022;61:3597. doi:10.1007/s00394-022-02904-0
Vázquez-Manjarrez N, Guevara-Cruz M, Flores-López A, Pichardo-Ontiveros E, Tovar AR, et al. Effect of a dietary intervention with functional foods on LDL-C concentrations and lipoprotein subclasses in overweight subjects with hypercholesterolemia: Results of a controlled trial. Clin Nutr. 2021;40:2527. doi:10.1016/j.clnu.2021.02.048